Des Moines vs Iowa City: Registered Nurse Salary (2026)
Compare registered nurse salaries between Des Moines, IA and Iowa City, IA. All figures are 2026 estimates projected from BLS 2025 data.
Side-by-Side Comparison
| Metric | Des Moines, IA | Iowa City, IA |
|---|---|---|
| Median Salary | $82,805 | $90,503▲ |
| Hourly Rate | $39.81 | $43.51▲ |
| Entry Level (P10) | $68,115 | $74,022▲ |
| 25th Percentile | $73,791 | $74,022▲ |
| 75th Percentile | $91,293 | $97,622▲ |
| Top Earner (P90) | $105,837 | $111,787▲ |
| Total Employed | 8,130▲ | 4,090 |
Verdict
Iowa City, IA offers better overall compensation for registered nurses, winning 3 out of 4 metrics compared to Des Moines.
The salary gap between Des Moines and Iowa City is $7,698 (9.30%). Iowa City's median is -11.90% compared to the US national median of $102,730.
Salary Range Comparison
The full salary range (10th to 90th percentile) in Des Moines spans $37,722,Iowa City spans $37,765. Iowa City has a wider pay range, suggesting more variation in pay between entry-level and experienced registered nurses.
Cost-of-Living Adjusted Comparison
After cost-of-living adjustment, Iowa City ($98,901 effective) pays 9.53% more than Des Moines ($90,299 effective).
Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.
Which City Is Right for You?
Choose Des Moines if…
- ✓Larger job market (8,130 employed)
- ✓You prefer the Iowa area and lifestyle
Choose Iowa City if…
- ✓Higher median salary ($90,503/year)
- ✓Better top-earner potential ($111,787)
- ✓Better purchasing power (CoL-adjusted: $98,901)
- ✓You prefer the Iowa area and lifestyle
Historical Salary Growth Comparison
Based on BLS OEWS metropolitan area data, registered nurse salaries in Des Moines grew 28.5% from 2019 to 2025, compared to 31.4% growth in Iowa City over the same period.
Des Moines, IA
$61,170 (2019) → $78,630 (2025)
Iowa City, IA
$65,390 (2019) → $85,940 (2025)
View Full Salary Data
Des Moines, IA
Iowa City, IA
Frequently Asked Questions
Which city pays registered nurses more: Des Moines or Iowa City?
What is the hourly rate difference between Des Moines and Iowa City?
Should I relocate from Des Moines to Iowa City as a registered nurse?
What do entry-level registered nurses earn in Des Moines vs Iowa City?
Written by Jordan Lee, RN, BSN
Career Analyst
Jordan Lee has 10 years of experience as a registered nurse. Their specialty is pediatric nursing in a community hospital. They analyze nursing workforce trends and salary data.
Methodology & Data Source
All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.31% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.
Data Sources & Methodology
Source: BLS, OEWS , released .
Compiled and verified by Jordan Lee, RN, BSN, a licensed registered nurse with 10+ years of clinical experience. · View source data at BLS.gov