Registered Nurse Salary

Houston vs Seguin: Registered Nurse Salary (2026)

Compare registered nurse salaries between Houston, TX and Seguin, TX. All figures are 2026 estimates projected from BLS 2025 data.

Houston, TX
$105,131
$50.55/hr
Seguin, TX
$83,534
$40.17/hr

Side-by-Side Comparison

MetricHouston, TXSeguin, TX
Median Salary$105,131$83,534
Hourly Rate$50.55$40.17
Entry Level (P10)$78,835$63,479
25th Percentile$86,238$71,207
75th Percentile$122,160$95,745
Top Earner (P90)$137,366$114,906
Total Employed65,9107
Side-by-side bar chart comparing Houston ($105,131) and Seguin ($83,534) registered nurse salaries.HoustonSeguinMedian Salary$105,131$83,534Entry Level (P10)$78,835$63,479Top Earner (P90)$137,366$114,906US Median $102,730

Verdict

Houston, TX offers better overall compensation for registered nurses, winning 4 out of 4 metrics compared to Seguin.

The salary gap between Houston and Seguin is $21,597 (25.85%). Houston's median is +2.34% compared to the US national median of $102,730.

Salary Range Comparison

The full salary range (10th to 90th percentile) in Houston spans $58,531,Seguin spans $51,427. Houston has a wider pay range, meaning more potential for high earners but also more variation.

Houston
P10 (Entry)$78,835
P25$86,238
Median$105,131
P75$122,160
P90 (Top)$137,366
Seguin
P10 (Entry)$63,479
P25$71,207
Median$83,534
P75$95,745
P90 (Top)$114,906

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, Houston ($106,592 effective) pays 22.50% more than Seguin ($87,015 effective).

Houston
Nominal: $105,131
CoL Index: 98.629
Adjusted: $106,592
Seguin
Nominal: $83,534
CoL Index: 96
Adjusted: $87,015

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose Houston if…

  • Higher median salary ($105,131/year)
  • Better top-earner potential ($137,366)
  • Larger job market (65,910 employed)
  • Better purchasing power (CoL-adjusted: $106,592)
  • You prefer the Texas area and lifestyle

Choose Seguin if…

  • You prefer the Texas area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, registered nurse salaries in Houston grew 23.8% from 2019 to 2025, compared to 1.0% growth in Seguin over the same period.

Houston, TX

+23.8%

$80,640 (2019) → $99,830 (2025)

Seguin, TX

+1.0%

$78,547 (2024) → $79,322 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays registered nurses more: Houston or Seguin?

Houston has a higher median registered nurse salary at $105,131/year, compared to Seguin at $83,534/year — a difference of $21,597 (25.85%).

What is the hourly rate difference between Houston and Seguin?

Houston registered nurses earn $50.55/hr while Seguin hygienists earn $40.17/hr (2026 est.).

Should I relocate from Houston to Seguin as a registered nurse?

Consider more than just salary when comparing Houston and Seguin. Factor in cost of living (CoL-adjusted: Houston = $106,592, Seguin = $87,015), job availability (65,910 vs 7 employed), commute, and career growth potential.

What do entry-level registered nurses earn in Houston vs Seguin?

Entry-level (10th percentile) registered nurses earn $78,835 in Houston and $63,479 in Seguin. The Houston area offers higher starting salaries.

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JL

Written by Jordan Lee, RN, BSN

Career Analyst

Jordan Lee has 10 years of experience as a registered nurse. Their specialty is pediatric nursing in a community hospital. They analyze nursing workforce trends and salary data.

Clinically reviewed by Amina Patel, RN, MSNData verified by Carlos Gomez, RN, DNP

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.31% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Jordan Lee, RN, BSN, a licensed registered nurse with 10+ years of clinical experience. · View source data at BLS.gov