Registered Nurse Salary

Indio vs San Francisco: Registered Nurse Salary (2026)

Compare registered nurse salaries between Indio, CA and San Francisco, CA. All figures are 2026 estimates projected from BLS 2025 data.

Indio, CA
$139,318
$66.98/hr
San Francisco, CA
$196,519
$94.47/hr

Side-by-Side Comparison

MetricIndio, CASan Francisco, CA
Median Salary$139,318$196,519
Hourly Rate$66.98$94.47
Entry Level (P10)$102,122$125,624
25th Percentile$116,858$144,401
75th Percentile$161,919$227,080
Top Earner (P90)$197,746$235,652
Total Employed2341,750
Side-by-side bar chart comparing Indio ($139,318) and San Francisco ($196,519) registered nurse salaries.IndioSan FranciscoMedian Salary$139,318$196,519Entry Level (P10)$102,122$125,624Top Earner (P90)$197,746$235,652US Median $102,730

Verdict

San Francisco, CA offers better overall compensation for registered nurses, winning 4 out of 4 metrics compared to Indio.

The salary gap between Indio and San Francisco is $57,201 (41.06%). San Francisco's median is +91.30% compared to the US national median of $102,730.

Salary Range Comparison

The full salary range (10th to 90th percentile) in Indio spans $95,624,San Francisco spans $110,028. San Francisco has a wider pay range, suggesting more variation in pay between entry-level and experienced registered nurses.

Indio
P10 (Entry)$102,122
P25$116,858
Median$139,318
P75$161,919
P90 (Top)$197,746
San Francisco
P10 (Entry)$125,624
P25$144,401
Median$196,519
P75$227,080
P90 (Top)$235,652

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, San Francisco ($169,980 effective) pays 37.99% more than Indio ($123,181 effective).

Indio
Nominal: $139,318
CoL Index: 113.1
Adjusted: $123,181
San Francisco
Nominal: $196,519
CoL Index: 115.613
Adjusted: $169,980

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose Indio if…

  • You prefer the California area and lifestyle

Choose San Francisco if…

  • Higher median salary ($196,519/year)
  • Better top-earner potential ($235,652)
  • Larger job market (41,750 employed)
  • Better purchasing power (CoL-adjusted: $169,980)
  • You prefer the California area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, registered nurse salaries in Indio grew -13.0% from 2024 to 2025, compared to 31.7% growth in San Francisco over the same period.

Indio, CA

+-13.0%

$152,127 (2024) → $132,293 (2025)

San Francisco, CA

+31.7%

$141,640 (2019) → $186,610 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays registered nurses more: Indio or San Francisco?

San Francisco has a higher median registered nurse salary at $196,519/year, compared to Indio at $139,318/year — a difference of $57,201 (41.06%).

What is the hourly rate difference between Indio and San Francisco?

Indio registered nurses earn $66.98/hr while San Francisco hygienists earn $94.47/hr (2026 est.).

Should I relocate from Indio to San Francisco as a registered nurse?

Consider more than just salary when comparing Indio and San Francisco. Factor in cost of living (CoL-adjusted: Indio = $123,181, San Francisco = $169,980), job availability (23 vs 41,750 employed), commute, and career growth potential.

What do entry-level registered nurses earn in Indio vs San Francisco?

Entry-level (10th percentile) registered nurses earn $102,122 in Indio and $125,624 in San Francisco. The San Francisco area offers higher starting salaries.

Related Comparisons

JL

Written by Jordan Lee, RN, BSN

Career Analyst

Jordan Lee has 10 years of experience as a registered nurse. Their specialty is pediatric nursing in a community hospital. They analyze nursing workforce trends and salary data.

Clinically reviewed by Amina Patel, RN, MSNData verified by Carlos Gomez, RN, DNP

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.31% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Jordan Lee, RN, BSN, a licensed registered nurse with 10+ years of clinical experience. · View source data at BLS.gov