Registered Nurse Salary

San Diego vs San Jose: Registered Nurse Salary (2026)

Compare registered nurse salaries between San Diego, CA and San Jose, CA. All figures are 2026 estimates projected from BLS 2025 data.

San Diego, CA
$146,929
$70.64/hr
San Jose, CA
$228,249
$109.73/hr

Side-by-Side Comparison

MetricSan Diego, CASan Jose, CA
Median Salary$146,929$228,249
Hourly Rate$70.64$109.73
Entry Level (P10)$107,922$130,732
25th Percentile$135,197$173,814
75th Percentile$178,943$235,378
Top Earner (P90)$184,514$247,679
Total Employed28,68022,930
Side-by-side bar chart comparing San Diego ($146,929) and San Jose ($228,249) registered nurse salaries.San DiegoSan JoseMedian Salary$146,929$228,249Entry Level (P10)$107,922$130,732Top Earner (P90)$184,514$247,679US Median $102,730

Verdict

San Jose, CA offers better overall compensation for registered nurses, winning 3 out of 4 metrics compared to San Diego.

The salary gap between San Diego and San Jose is $81,320 (55.35%). San Jose's median is +122.18% compared to the US national median of $102,730.

Salary Range Comparison

The full salary range (10th to 90th percentile) in San Diego spans $76,592,San Jose spans $116,947. San Jose has a wider pay range, suggesting more variation in pay between entry-level and experienced registered nurses.

San Diego
P10 (Entry)$107,922
P25$135,197
Median$146,929
P75$178,943
P90 (Top)$184,514
San Jose
P10 (Entry)$130,732
P25$173,814
Median$228,249
P75$235,378
P90 (Top)$247,679

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, San Jose ($206,704 effective) pays 57.41% more than San Diego ($131,319 effective).

San Diego
Nominal: $146,929
CoL Index: 111.887
Adjusted: $131,319
San Jose
Nominal: $228,249
CoL Index: 110.423
Adjusted: $206,704

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose San Diego if…

  • Larger job market (28,680 employed)
  • You prefer the California area and lifestyle

Choose San Jose if…

  • Higher median salary ($228,249/year)
  • Better top-earner potential ($247,679)
  • Better purchasing power (CoL-adjusted: $206,704)
  • You prefer the California area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, registered nurse salaries in San Diego grew 32.7% from 2019 to 2025, compared to 48.1% growth in San Jose over the same period.

San Diego, CA

+32.7%

$105,100 (2019) → $139,520 (2025)

San Jose, CA

+48.1%

$146,380 (2019) → $216,740 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays registered nurses more: San Diego or San Jose?

San Jose has a higher median registered nurse salary at $228,249/year, compared to San Diego at $146,929/year — a difference of $81,320 (55.35%).

What is the hourly rate difference between San Diego and San Jose?

San Diego registered nurses earn $70.64/hr while San Jose hygienists earn $109.73/hr (2026 est.).

Should I relocate from San Diego to San Jose as a registered nurse?

Consider more than just salary when comparing San Diego and San Jose. Factor in cost of living (CoL-adjusted: San Diego = $131,319, San Jose = $206,704), job availability (28,680 vs 22,930 employed), commute, and career growth potential.

What do entry-level registered nurses earn in San Diego vs San Jose?

Entry-level (10th percentile) registered nurses earn $107,922 in San Diego and $130,732 in San Jose. The San Jose area offers higher starting salaries.

Related Comparisons

JL

Written by Jordan Lee, RN, BSN

Career Analyst

Jordan Lee has 10 years of experience as a registered nurse. Their specialty is pediatric nursing in a community hospital. They analyze nursing workforce trends and salary data.

Clinically reviewed by Amina Patel, RN, MSNData verified by Carlos Gomez, RN, DNP

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.31% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Jordan Lee, RN, BSN, a licensed registered nurse with 10+ years of clinical experience. · View source data at BLS.gov