Registered Nurse Hourly Pay in Greenville, SC: $41.22 (2026)
Quick Answer:Hourly pay for a registered nurse working in Greenville, SC runs $41.22 at the median for 2026 — annualizing to $85,722 at a standard 2,080-hour year. Figures projected from BLS OEWS 2025 (SOC 29-1141). Weighted against Greenville's regional price level (BEA RPP 93.3, 7% below national), each hour of work buys what $44.20 nationally would. A 24-hour part-time schedule grosses $51,440 per year.
Official BLS data · View source
Registered nurses in Greenville, South Carolina, earn a median hourly pay of $41.22, which falls short of the national hourly median of $49.39. This discrepancy indicates that nursing professionals in the area may face more financial constraints, particularly when working part-time or in per-diem roles. Those typical settings—spanning hospital floors, intensive care units, emergency departments, and outpatient clinics—can offer varied experiences. With an hourly pay range from $34.70 for entry-level positions to $50.95 for the highest earners, registered nurses in Greenville have the opportunity to gain valuable experience while working flexible schedules tailored to their lifestyle, particularly for those pursuing part-time positions or per-diem shifts.
Registered Nurse Hourly Wage Breakdown
| Percentile | Hourly Rate | Per 8hr Shift |
|---|---|---|
| Entry Level (P10) | $34.70 | $277.60 |
| Lower Range (P25) | $39.52 | $316.18 |
| Median (P50) | $41.22 | $329.75 |
| Upper Range (P75) | $48.90 | $391.16 |
| Top Earners (P90) | $50.95 | $407.59 |
Estimated Annual Income by Work Schedule in Greenville
Based on $41.22/hr median hourly rate · 2026 est.
At $41.22/hr, a registered nurse working full-time (40 hr/wk) in Greenville, SC can expect to earn approximately $85,734 per year (2026 est.). Part-time hygienists working 24 hours per week would earn around $49,462. With a cost-of-living index of 93.26 (below the national average), these earnings stretch further in Greenville.
Hourly Rate Calculator
Schedule Comparison in Greenville
| Schedule | Weekly | Monthly | Annual |
|---|---|---|---|
| Full-Time (40 hrs) | $1,648.73 | $7,145 | $85,734 |
| Part-Time (24 hrs) | $989.24 | $4,287 | $51,440 |
| Per Diem (16 hrs) | $659.49 | $2,858 | $34,294 |
Compare RN Wages With Similar Roles
| Role | Median Hourly |
|---|---|
| Registered Nurse (Greenville) | $41.22 |
| Licensed Practical Nurse (National Avg) | $29.34 |
| Nursing Assistant (CNA) (National Avg) | $18.60 |
| Nurse Practitioner (National Avg) | $63.50 |
| Medical Assistant (National Avg) | $19.70 |
Registered Nurses in Greenville, SC earn a median of $85,722 per year (2026 est.), which is 16.56% lower than the national median of $102,730 and 0.30% below the South Carolina state average of $85,980.
Registered Nurse Hourly Pay vs. Cost of Living
Working 24h/week at $41.22/hr = $51,440/year (purchasing power: $55,158).
Working 40h/week (full-time) = $85,734/year (purchasing power: $91,930).
CoL index: 93.26 (100 = national average). Your dollars stretch further here.
2019 BLS Actual
$29.58/hr
2025 BLS Actual
$39.14/hr
2026 Current Est.
$41.22/hr
2019–2027 Growth
+46.7%
Hourly Rate Trajectory for Registered Nurses in Greenville (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 5.31% projection.
| Year | Hourly Rate | Status |
|---|---|---|
| 2019 | $29.58/hr | Actual |
| 2020 | $31.00/hr | Actual |
| 2021 | $29.98/hr | Actual |
| 2022 | $36.39/hr | Actual |
| 2023 | $36.78/hr | Actual |
| 2024 | $38.26/hr | Actual |
| 2025 | $39.14/hr | Actual |
| 2026(current) | $41.22/hr | Estimated |
| 2027 | $43.41/hr | Projected |
Based on 7 years of BLS OEWS metropolitan area data, the median hourly rate for registered nurses in Greenville grew 32.3% from $29.58/hr (2019) to $39.14/hr (2025). At a 5.31% projected growth rate, hourly pay is expected to reach $43.41/hr by 2027. Part-time and per-diem registered nurses can use this multi-year trend to benchmark future contract negotiations.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Greenville metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 5.31% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Working as an Hourly Registered Nurse in Greenville
For those considering part-time opportunities in Greenville, a registered nurse working three days a week, clocking in at 24 hours, would see a take-home pay that reflects the reduced hours compared to full-time positions. Many per-diem registered nurses typically command higher rates, often billing between $50 and $80 an hour, making it a lucrative option especially within specialized units. Travel nursing has also become increasingly popular, with contracts offering substantial weekly pay, sometimes reaching $5,000 to $8,000 in high-demand situations, which could significantly outweigh the traditional hourly pay. Hourly rates can fluctuate depending on the type of employer, with hospitals, surgical centers, home health agencies, and ambulatory clinics all offering different compensation structures. Registered nurses should weigh the benefits of higher hourly rates without additional perks versus positions that guarantee health insurance and retirement plans. Understanding these nuances is crucial for effective negotiation in Greenville’s unique healthcare market.
More salary data for Greenville, SC:
Frequently Asked Questions
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Written by Jordan Lee, RN, BSN
Career Analyst
Jordan Lee has 10 years of experience as a registered nurse. Their specialty is pediatric nursing in a community hospital. They analyze nursing workforce trends and salary data.
Methodology & Data Source
Hourly wage figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. A 5.31% compound annual growth rate (CAGR), derived from 6-year national BLS wage trends, was applied to estimate current 2026 hourly rates for registered nurses in Greenville. Part-time and full-time income estimates assume consistent weekly hours and do not account for overtime, benefits, or seasonal variation.
Data Sources & Methodology
Source: BLS, OEWS, 7-year dataset (–). Per-city data from annual BLS metropolitan area surveys.
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 5.31%, derived from historical BLS wage trends for registered nurses (SOC 29-1141).
Compiled and verified by Jordan Lee, RN, BSN, a licensed registered nurse with 10+ years of clinical experience. · View source data at BLS.gov