Registered Nurse Salary

Chicago vs O'Fallon: Registered Nurse Salary (2026)

Compare registered nurse salaries between Chicago, IL and O'Fallon, IL. All figures are 2026 estimates projected from BLS 2025 data.

Chicago, IL
$105,826
$50.88/hr
O'Fallon, IL
$87,433
$42.04/hr

Side-by-Side Comparison

MetricChicago, ILO'Fallon, IL
Median Salary$105,826$87,433
Hourly Rate$50.88$42.04
Entry Level (P10)$81,520$61,053
25th Percentile$87,028$70,483
75th Percentile$114,188$98,237
Top Earner (P90)$125,593$122,305
Total Employed100,2406
Side-by-side bar chart comparing Chicago ($105,826) and O'Fallon ($87,433) registered nurse salaries.ChicagoO'FallonMedian Salary$105,826$87,433Entry Level (P10)$81,520$61,053Top Earner (P90)$125,593$122,305US Median $102,730

Verdict

Chicago, IL offers better overall compensation for registered nurses, winning 4 out of 4 metrics compared to O'Fallon.

The salary gap between Chicago and O'Fallon is $18,393 (21.04%). Chicago's median is +3.01% compared to the US national median of $102,730.

Salary Range Comparison

The full salary range (10th to 90th percentile) in Chicago spans $44,073,O'Fallon spans $61,252. O'Fallon has a wider pay range, suggesting more variation in pay between entry-level and experienced registered nurses.

Chicago
P10 (Entry)$81,520
P25$87,028
Median$105,826
P75$114,188
P90 (Top)$125,593
O'Fallon
P10 (Entry)$61,053
P25$70,483
Median$87,433
P75$98,237
P90 (Top)$122,305

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, Chicago ($102,154 effective) pays 13.45% more than O'Fallon ($90,044 effective).

Chicago
Nominal: $105,826
CoL Index: 103.595
Adjusted: $102,154
O'Fallon
Nominal: $87,433
CoL Index: 97.1
Adjusted: $90,044

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose Chicago if…

  • Higher median salary ($105,826/year)
  • Better top-earner potential ($125,593)
  • Larger job market (100,240 employed)
  • Better purchasing power (CoL-adjusted: $102,154)
  • You prefer the Illinois area and lifestyle

Choose O'Fallon if…

  • You prefer the Illinois area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, registered nurse salaries in Chicago grew 32.7% from 2019 to 2025, compared to 3.3% growth in O'Fallon over the same period.

Chicago, IL

+32.7%

$75,700 (2019) → $100,490 (2025)

O'Fallon, IL

+3.3%

$80,408 (2024) → $83,024 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays registered nurses more: Chicago or O'Fallon?

Chicago has a higher median registered nurse salary at $105,826/year, compared to O'Fallon at $87,433/year — a difference of $18,393 (21.04%).

What is the hourly rate difference between Chicago and O'Fallon?

Chicago registered nurses earn $50.88/hr while O'Fallon hygienists earn $42.04/hr (2026 est.).

Should I relocate from Chicago to O'Fallon as a registered nurse?

Consider more than just salary when comparing Chicago and O'Fallon. Factor in cost of living (CoL-adjusted: Chicago = $102,154, O'Fallon = $90,044), job availability (100,240 vs 6 employed), commute, and career growth potential.

What do entry-level registered nurses earn in Chicago vs O'Fallon?

Entry-level (10th percentile) registered nurses earn $81,520 in Chicago and $61,053 in O'Fallon. The Chicago area offers higher starting salaries.

Related Comparisons

JL

Written by Jordan Lee, RN, BSN

Career Analyst

Jordan Lee has 10 years of experience as a registered nurse. Their specialty is pediatric nursing in a community hospital. They analyze nursing workforce trends and salary data.

Clinically reviewed by Amina Patel, RN, MSNData verified by Carlos Gomez, RN, DNP

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.31% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Jordan Lee, RN, BSN, a licensed registered nurse with 10+ years of clinical experience. · View source data at BLS.gov